... mechanotransduction Alpha-catenin Convergent extension Embryogenesis During embryonic development, tissue shape and organization is established by a series of complex cell migrations and rearrangements. These developmental cell-movement processes are largely dependent on dynamic intercellular adhesions...

... and -11 exhibited distinct noncanonical Wnt activities by disturbing convergent extension movements. However, NvWnt-5 rescued XWnt-11 and NvWnt-11 specifically XWnt-5a depleted embryos. This unexpected ‘inverse’ activity suggests that specific structures in Wnt ligands are important for receptor complex...