... attributed. Summary: Basement membranes (BMs) are critical for morphogenesis. This Review provides an overview of the mechanisms by which BMs can be remodelled to regulate the shape of tissues and organs. Extracellular matrix Laminin Collagen Nidogen Perlecan Deutsche...

... (cyclic muscle length changes) were then performed about optimal muscle length (L O ) at 1.5–3-Hz cycle frequencies and 1–7-mm length changes. Muscles were then fixed in formalin at L O . Fascicle lengths and sarcomere lengths were measured to calculate SSN. Intramuscular collagen content and crosslinking...

..., and fragmented collagen fibers compared with those of the rat. Additionally, the cotton-rat tail was easily torn, with minimum bleeding. The median coccygeal artery of the cotton rat had a thick smooth muscle layer, and its lumen was filled with the peeled intima with fibrin coagulation, which might...

... Collagen HREM DMDD Rare diseases The Deciphering the Mechanisms of Developmental Disorders (DMDD) program is an international, systematic effort to identify and characterise the phenotypes of mouse embryos carrying embryonic or perinatal lethal mutations ( Dickinson et al., 2016 ; Geyer et al...

... the prostatic consequences of activating or inhibiting Edar expression. Edar overexpression does not visibly alter prostatic bud formation or branching morphogenesis, and Edar expression is not necessary for either of these events. However, Edar overexpression is associated with an abnormally thick and collagen...

... cells and renal fibroblasts in response to cytokine stimulation. Whilst fibroblasts produced a higher basal level of extracellular matrix components, epithelial cells were able to deposit significant levels of fibronectin, collagen I, III and IV in response to cytokine stimulation. In response...

... of the extracellular matrix in ascidian embryos and larvae, providing clues for its function in chordate development. Ciona Extracellular matrix Collagen RNA sequencing The extracellular matrix (ECM) is the fundamental cellular component of multicellular organisms. It is secreted from...