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Keywords: Chromatin
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Journal Articles
Biol Open (2021) 10 (5): bio057729.
Published: 26 May 2021
... to hydroxyurea-induced replication stress tolerance, in part by regulating expression of ribonuclease reductase subunit RRM2. Chromatin Drug tolerance Replication stress KDM5 proteins belong to the JUMONJI family of demethylases that catalyse the removal of methyl groups from lysine residues...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (7): bio041368.
Published: 10 July 2019
...Mei-Zi Zhang; Xiao-Min Cao; Feng-Qin Xu; Xiao-Wei Liang; Long-Long Fu; Bao Li; Wei-Guang Liu; Shuo-Guo Li; Fang-Zhen Sun; Xiu-Ying Huang; Wei-Hong Huang ABSTRACT In human sperm, a fraction of its chromatin retains nucleosomes that are positioned on specific sequences containing genes and regulatory...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (11): bio036632.
Published: 31 October 2018
... and positioning of organelles. One of the major findings was the anisotropic and subtype-specific growth of the different PRC compartments. In addition, a transient accumulation of endoplasmic reticulum in rod PRCs, changes in chromatin organisation in UV sensitive cones and differential expression of polarity...
Includes: Supplementary data
Journal Articles
Biol Open (2018) 7 (5): bio031245.
Published: 10 May 2018
... during differentiation by removing H3K4me3 from promoters of self-renewal and TS cell enriched genes. Trophoblast stem cells Multipotent Epigenetics Chromatin ChIP-Seq KDM5B H3K4me3 Differentiation Histone demethylase The formation of pre-implantation stage blastocysts involves...
Journal Articles
Biol Open (2018) 7 (3): bio031476.
Published: 23 March 2018
...Alice Sherrard; Paul Bishop; Melanie Panagi; Maria Beatriz Villagomez; Dominic Alibhai; Abderrahmane Kaidi ABSTRACT Changes in chromatin structure are key determinants of genomic responses. Thus, methods that enable such measurements are instrumental for investigating genome regulation and function...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (9): 1177–1188.
Published: 26 August 2016
... Transgenerational Small RNAs Chromatin Most models of evolution, which are based on Mendelian genetics, depend conceptually on the existence of a distinct separation between generations across an ancestry. This distinction between parents and children is supposedly enforced by Weismann's barrier, which...
Journal Articles
Biol Open (2016) 5 (3): 372–380.
Published: 24 February 2016
...Thomas W. Flanagan; Jacob K. Files; Kelsey Rose Casano; Eric M. George; David T. Brown ABSTRACT Mammals express six major somatic linker histone subtypes, all of which display dynamic binding to chromatin, characterized by transient binding at a given location followed by rapid translocation...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (12): 1158–1163.
Published: 13 November 2014
.../by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. ATRX Cell division Chromatin Cortical lamination Neurodevelopment The ATRX protein belongs to a family of SWI/SNF2-type chromatin remodeling...
Journal Articles
Biol Open (2014) 3 (9): 794–802.
Published: 1 August 2014
... with gene transcription in animals and plants. In animals, H3.3 is deposited into chromatin by specific protein complexes, including the HIRA complex. H3.3 variants evolved independently and acquired similar properties in animals and plants, questioning how the H3.3 deposition machinery evolved in plants...
Includes: Supplementary data
Journal Articles
Biol Open (2012) 1 (4): 341–352.
Published: 7 February 2012
... chromatin remodeling: genetics, genomics and mechanisms. Cell Res. 21 , 396 – 420 . 10.1038/cr.2011.32 Hendrich B. , Guy J. , Ramsahoye B. , Wilson V. A. , Bird A. ( 2001 ). Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse...
Includes: Supplementary data