... of the mouse cerebral cortex. We used a conditional gene knockout strategy (Raldh2cKO) ablating the function of a RA-synthesizing enzyme in the developing meninges, and found that this loss-of-function affects cortical layering: the deep layers (V and VI) are increased, whereas layer IV contains fewer RORβ...

...Hiroshi Kawasaki; Tomohisa Toda; Kaori Tanno Summary Brain structures such as the outer subventricular zone (OSVZ) and the inner fiber layer (IFL) in the developing cerebral cortex are especially prominent in higher mammals. However, the molecular mechanisms underlying the formation of the OSVZ...