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Keywords: Central nervous system
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Journal Articles

Shared and unique consequences of Joubert Syndrome gene dysfunction on the zebrafish central nervous system

Alexandra R. Noble, Markus Masek, Claudia Hofmann, Arianna Cuoco, Tamara D. S. Rusterholz, Hayriye Özkoc, Nadja R. Greter, Ian G. Phelps, Nikita Vladimirov, Sepp Kollmorgen, Esther Stoeckli, Ruxandra Bachmann-Gagescu
Journal: Biology Open
Biol Open (2024) 13 (11): bio060421.
https://doi.org/10.1242/bio.060421
Published: 12 November 2024
... gene bbs1 k742 . We identified no commonly dysregulated signalling pathways in these mutants and yet all mutants displayed an enrichment of altered gene sets related to central nervous system function. We found that JBTS mutants have altered primary cilia throughout the brain but do not display...
View article titled, Shared and unique consequences of Joubert Syndrome gene dysfunction on the zebrafish <span class="search-highlight">central</span> <span class="search-highlight">nervous</span> <span class="search-highlight">system</span>
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Includes: Supplementary data
Journal Articles

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish

Isabel Reuter, Jana Jäckels, Susanne Kneitz, Jochen Kuper, Klaus-Peter Lesch, Christina Lillesaar
Journal: Biology Open
Biol Open (2019) 8 (6): bio040683.
https://doi.org/10.1242/bio.040683
Published: 5 June 2019
... of hypothalamic monoaminergic cells in zebrafish. Fgf-signalling Serotonin Dopamine Hypothalamus Central nervous system Serotonin (5-hydroxytryptamine, 5-HT) is an ancient signalling molecule present in the nervous system of animals from cnidarian and bilaterian lineages ( Hay-Schmidt, 2000...
View article titled, Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish
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Includes: Supplementary data
Journal Articles

Effect of intracerebroventricular epinephrine microinjection on blood pressure and urinary sodium handling in gestational protein-restricted male adult rat offspring

Bárbara Vaccari Cardoso, Augusto Henrique Custódio, Patrícia Aline Boer, José Antonio Rocha Gontijo
Journal: Biology Open
Biol Open (2019) 8 (4): bio038562.
https://doi.org/10.1242/bio.038562
Published: 1 April 2019
... of central adrenergic receptors’ interaction on hypertension pathogenesis in maternal LP fetal-programming offspring. This study also provides good evidence for the existence of central nervous system adrenergic mechanisms consisting of α1 and α2-adrenoceptors, which work reciprocally on the control of renal...
View article titled, Effect of intracerebroventricular epinephrine microinjection on blood pressure and urinary sodium handling in gestational protein-restricted male adult rat offspring
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Journal Articles

Spatio-temporal neural stem cell behavior leads to both perfect and imperfect structural brain regeneration in adult newts

Yuko Urata, Wataru Yamashita, Takeshi Inoue, Kiyokazu Agata
Journal: Biology Open
Biol Open (2018) 7 (6): bio033142.
https://doi.org/10.1242/bio.033142
Published: 25 June 2018
.... ( 2001 ). Role of Pax3/7 in the tectum regionalization . Development   128 , 4069 - 4077 . Mchedlishvili , L. , Mazurov , V. and Tanaka , E. M. ( 2012 ). Reconstitution of the central nervous system during salamander tail regeneration from the implanted neurospheres...
View article titled, Spatio-temporal neural stem cell behavior leads to both perfect and imperfect structural brain regeneration in adult newts
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Includes: Supplementary data
Journal Articles

The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B

M. Moris-Sanz, A. Estacio-Gómez, E. Sánchez-Herrero, F. J. Díaz-Benjumea
Journal: Biology Open
Biol Open (2015) 4 (9): 1132–1142.
https://doi.org/10.1242/bio.012872
Published: 14 August 2015
...M. Moris-Sanz; A. Estacio-Gómez; E. Sánchez-Herrero; F. J. Díaz-Benjumea ABSTRACT During development, HOX genes play critical roles in the establishment of segmental differences. In the Drosophila central nervous system, these differences are manifested in the number and type of neurons generated...
View article titled, The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B
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Includes: Supplementary data