.... B. , Davidson , M. W. , Hess , H. F. and Waterman , C. M. ( 2010 ). Nanoscale architecture of integrin-based cell adhesions . Nature   468 , 580 - 584 . 10.1038/nature09621 Laukaitis , C. M. , Webb , D. J. , Donais , K. and Horwitz , A. F. ( 2001...

...Zahra Erami; Paul Timpson; Wu Yao; Ronen Zaidel-Bar; Kurt I. Anderson ABSTRACT E-cadherin is a trans-membrane tumor suppressor responsible for epithelial cell adhesion. E-cadherin forms adhesive clusters through combined extra-cellular cis- and trans-interactions and intracellular interaction...

... with cell adhesion can cause severe defects in neuronal migration and axon guidance. In this study we have analyzed the function of the MAM domain containing glycosylphosphatidylinositol anchor 2A (MDGA2A) protein in zebrafish cranial motoneuron development. MDGA2A is prominently expressed in distinct...

...-5 retards spine maturation by preventing reorganization of the actin cytoskeleton, but NMDA receptor activation is sufficient to relieve the brake and promote the maturation of spines. ICAM-5 Integrin Actinin Cell adhesion Spine maturation The C57B/l6 mouse strain was used...

... localized at cell adhesions in complex with focal adhesion kinase and enhanced stability and maturation of cell adhesions. In addition, p85β induced development at cell adhesions of an F-actin core that extended several microns into the cell z-axis resembling the skeleton of invadopodia. p85β lead to F...

.... Lastly, the most consistent and striking observation was that differentiated cells sorted to the surface and formed an enveloping layer, regardless of the relative cell adhesive affinity of any cell combination, supporting the hypothesis that the ability of the differentiated cells to establish apical...

... fibronectin, and a reduced adhesion to somatic endodermal cells. Data obtained from qPCR analysis with isolated PGCs reveal that down-regulation of E-cadherin might contribute to this weakening of cell-cell adhesion. Interestingly, however, using an in vitro migration assay, we found that movement of X...

... and gastrulation. Epiboly mechanisms include blastomere radial intercalation cell movements and yolk cell microtubule cytoskeleton pulling the embryo to the vegetal pole. Both of these processes were disrupted by ethanol exposure. Ethanol effects on cell migration also indicated that cell adhesion was affected...

..., n  = 30 cells) substrates. Cardiomyocyte Traction force microscopy Cell adhesion Mechanoresponse Myofibril Sarcomere Mechanical properties of tissues strongly affect embedded mammalian cells. The consequences extend from simple, small adaptations of rather isolated cellular...