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Keywords: Cdc20
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Journal Articles

A novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1

Open Access
Marie Duranteau, Jean-Jacques Montagne, Zohra Rahmani
Journal: Biology Open
Biol Open (2016) 5 (11): 1674–1679.
https://doi.org/10.1242/bio.021196
Published: 15 November 2016
... of BubR1 leads to accelerated mitosis. We previously found that mutation of the KEN1-box domain of Drosophila BubR1 ( bubR1-KEN1 mutant) affects the binding of BubR1 to Cdc20, the activating co-factor of the APC/C, and does not accelerate the mitotic timing despite resulting in a defective SAC, which...
View articletitled, A novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1
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Includes: Supplementary data