... was developed to show that CIZ1 extends the window of cardiomyocyte proliferation and reduces the impact of injury on cardiac function. Cardiac function Cardiomyocyte CIZ1 DNA replication Nuclear-matrix protein Heart disease is a leading cause of death in the developed world, with major...

... function (PRSW was 33% less than control). Reduction of arterial blood pressure and systolic cardiac function in response to rhEPO were blocked in rats pretreated with a non-selective inhibitor of nitric oxide synthase (L-NAME). In Experiment 4 , 24 hours after a permanent ligation of a coronary artery...