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Keywords: Cancer
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Journal Articles
Biol Open (2022) 11 (12): bio059396.
Published: 29 November 2022
...Angie Yu Ching Poon; Ryohichi Sugimura ABSTRACT The use of natural killer (NK) cells in cancer immunotherapy demonstrates promising potential, yet its efficacy is often limited due to the loss of tumor-killing capacity and lack of specificity in vivo . Here, we review current approaches to confer...
Journal Articles
Biol Open (2021) 10 (11): bio058623.
Published: 3 November 2021
...Rita Brás; Augusta Monteiro; Claudio E. Sunkel; Luís Pedro Resende ABSTRACT Aneuploidy has been strongly linked to cancer development, and published evidence has suggested that aneuploidy can have an oncogenic or a tumor suppressor role depending on the tissue context. Using the Drosophila midgut...
Includes: Supplementary data
Journal Articles
Biol Open (2020) 9 (9): bio053405.
Published: 29 September 2020
... describe the temporal organisation of the main cellular events that occur in GB, including cell-to-cell interactions, neurodegeneration and tumour microtubes expansion. Glia Cancer Glioblastoma Tumour microtubes JNK Neurodegeneration Glioblastoma multiforme (GB) is the most frequent...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (7): bio044362.
Published: 5 July 2019
... have been identified in numerous cancers. Crizotinib, a small molecule inhibitor of c-Met and ALK, is a Food and Drug Administration-approved drug with reported efficacy in the treatment of cancer. Tropomyosins (TPMs) are a family of actin filament-binding proteins. Altered TPM expression has been...
Journal Articles
Journal Articles
Journal Articles
Biol Open (2013) 2 (4): 379–386.
Published: 14 February 2013
... 7 1 2013 © 2013. Published by The Company of Biologists Ltd 2013 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License ( http://creativecommons.org/licenses/by-nc-sa/3.0/ ). Cancer Chromosome compaction...
Includes: Supplementary data