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Keywords: CCM
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Journal Articles
Zuzana Macek Jilkova, Justyna Lisowska, Sandra Manet, Claude Verdier, Valerie Deplano, Christian Geindreau, Eva Faurobert, Corinne Albigès-Rizo, Alain Duperray
Journal:
Biology Open
Biol Open (2014) 3 (12): 1228–1235.
Published: 28 November 2014
... show that overexpression of the CCM complex, an inhibitor of β1 integrin activation, blocks endothelial actin rearrangement and cell reorientation in response to shear stress similarly to β1 integrin silencing. Conversely, depletion of CCM2 protein leads to an elongated “shear-stress-like” phenotype...
