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Journal Articles

Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons

Catherine L. Kaminski, Debarghya Dutta Banik, Ligia B. Schmitd, Brian A. Pierchala
Journal: Biology Open
Biol Open (2024) 13 (11): bio060541.
https://doi.org/10.1242/bio.060541
Published: 11 November 2024
... significant numbers of apoptotic neurons out to P14, and neurogenesis was still present at P14 as well. In both the SCG and geniculate ganglion (GG), postnatal neurogenesis was dependent on apoptosis because little or no postnatal neurogenesis was observed in Bax -/- mice, in which apoptosis is eliminated...
View articletitled, Identification of a postnatal period of interdependent neurogenesis and apoptosis in peripheral neurons
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Includes: Supplementary data
Journal Articles

Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, γH2AX accumulation, and Bax/Bak-dependence

Isabel F. Masteika, Anvitha Sathya, Sachiko Homma, Bess M. Miller, Frederick M. Boyce, Jeffrey Boone Miller
Journal: Biology Open
Biol Open (2022) 11 (2): bio059145.
https://doi.org/10.1242/bio.059145
Published: 22 February 2022
... expression as indicated by nuclear accumulation of a shuttle-GFP reporter. Second, building on studies from other labs, we showed that phospho(Ser139)-H2AX (γH2AX), an indicator of double-strand DNA breaks, accumulated both in human FSHD1 myotube nuclei upon endogenous DUX4 expression and in Bax-/-;Bak...
View articletitled, Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, γH2AX accumulation, and Bax/Bak-dependence
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Includes: Supplementary data
Journal Articles

Bax-inhibiting peptide attenuates bleomycin-induced lung injury in mice

Kunihiro Suzuki, Toyoshi Yanagihara, Tetsuya Yokoyama, Takashige Maeyama, Saiko Ogata-Suetsugu, Masako Arimura-Omori, Hironori Mikumo, Naoki Hamada, Eiji Harada, Kazuyoshi Kuwano, Taishi Harada, Yoichi Nakanishi
Journal: Biology Open
Biol Open (2017) 6 (12): 1869–1875.
https://doi.org/10.1242/bio.026005
Published: 14 November 2017
...Kunihiro Suzuki; Toyoshi Yanagihara; Tetsuya Yokoyama; Takashige Maeyama; Saiko Ogata-Suetsugu; Masako Arimura-Omori; Hironori Mikumo; Naoki Hamada; Eiji Harada; Kazuyoshi Kuwano; Taishi Harada; Yoichi Nakanishi ABSTRACT Bax is a pro-apoptotic member of the Bcl-2 family of proteins, and plays...
View articletitled, Bax-inhibiting peptide attenuates bleomycin-induced lung injury in mice
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Includes: Supplementary data