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Keywords: Aurora B
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Journal Articles
Aisling O'Connor, Stefano Maffini, Michael D. Rainey, Agnieszka Kaczmarczyk, David Gaboriau, Andrea Musacchio, Corrado Santocanale
Journal:
Biology Open
Biol Open (2016) 5 (1): 11–19.
Published: 18 December 2015
... recent reports indicating that it can cooperate with either one of the major checkpoint kinases, Aurora B or MPS1. In this study, we assess the role of PLK1 in SAC maintenance. We find that in nocodazole-arrested U2OS cells, PLK1 activity is continuously required for maintaining Aurora B protein...
Includes: Supplementary data
Journal Articles
Journal:
Biology Open
Biol Open (2013) 2 (5): 479–486.
Published: 25 March 2013
... congression. The BUBR1:B56-PP2A complex opposes Aurora B kinase activity, since loss of the complex can be reverted by inhibiting Aurora B. Importantly, we show that the failure of BUBR1 to recruit B56-PP2A also contributes to the chromosome congression defects found in cells derived from patients...
Includes: Supplementary data
