.... The zebrafish ( Danio rerio ) has become an invaluable animal model in this regard. The attributes of the zebrafish are many, and have been extensively reviewed, for example Domínguez-Oliva et al., 2023 ; Hodgson et al., 2018 ; Jagadeeswaran et al., 2016 ; and Yoganantharjah and Gibert, 2017 ; the ease...

... mice are obese, diabetic, hypertriglyceridemic and anemic with liver steatosis on ultrasound, providing a model for studying the pathogenesis and management of metabolic syndrome, a growing global epidemic. TPRC1 Metabolic syndrome Calcium channel Diabetes Ultrasound Animal model...

... This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Animal model Surgical...

... and reproduction in any medium provided that the original work is properly attributed. Summary: The availability of a reproducible animal model using current and clinically representative materials will facilitate translational research for innovative therapeutic approaches for prosthetic joint infections...

... M1-like phenotypes M2-like phenotypes Pulmonary emphysema Animal model Chronic obstructive pulmonary disease (COPD) is an inflammatory disease characterized by an exacerbated inflammatory response and/or alveolar abnormalities usually caused by constant exposure to noxious particles...

..., which is characterized by progressive, distal-to-proximal degeneration of peripheral nerves. The cellular and molecular mechanisms that trigger DN are highly complex, heterogeneous and not completely known. Animal models have constituted a valuable tool for understanding diabetes pathophysiology...

... accompanied by obesity, hyperglycemia, insulin resistance (IR) and type 2 diabetes (T2D), for which numerous animal models have been generated in order to explore the pathogenesis and therapies of NAFLD. On the contrary, quite a number of NAFLD subjects, especially in Asian regions, are non-obese and non...

... attributed. Summary: We describe the establishment of a human TNFα transgenic arthritis mouse model with applications for understanding the role of TNFα in disease progression and developing therapeutic strategies. Animal model Transgenic TNFα Rheumatoid arthritis Synovial hyperplasia Drug...

... aspects of Sjögren's syndrome is the high sexual dimorphism with women affected 10-20 times more than men. It is nearly impossible to study the sexual dimorphic development of Sjögren's syndrome in human patients; therefore it is pertinent to develop an appropriate animal model which resembles human...

... temperature Animal model Xenopus laevis In order to survive, organisms respond to environmental changes by altering their expression patterns of genes and proteins. One of the most important environmental factors is temperature, which governs the distribution, behaviour, and physiological response...