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Keywords: Amyloid
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Journal Articles
Biol Open (2021) 10 (1): bio054627.
Published: 25 January 2021
... in murine models of Alzheimer's disease (AD) to export amyloid beta (Abeta) from the endothelial cells of the blood–brain barrier to the periphery, and that pharmaceutical activation of ABCC1 can reduce amyloid plaque deposition in the brain. Here, we show that ABCC1 is not only capable of exporting Abeta...
Includes: Supplementary data
Journal Articles
Biol Open (2019) 8 (7): bio044529.
Published: 10 July 2019
... PrDMot3-GFP or PrDPan1-GFP were grown in SC-Gal medium to induce GFP-fusion protein production and then transferred onto the same medium supplemented with 1M KCl. (C) Cells of the 74D-694 strain harboring the plasmid expressing PrDSup35-GFP, as well as containing or lacking prion amyloids of Sup35 ([PSI...
Includes: Supplementary data
Journal Articles
Biol Open (2016) 5 (6): 801–806.
Published: 23 May 2016
...Michael H. Hayes; Daniel L. Weeks ABSTRACT A hallmark of Alzheimer's, Huntington's and similar diseases is the assembly of proteins into amyloids rather than folding into their native state. There is an increasing appreciation that amyloids, under specific conditions, may be non-pathogenic. Here we...
Includes: Supplementary data
Journal Articles
Biol Open (2014) 3 (11): 1139–1149.
Published: 31 October 2014
... in any medium provided that the original work is properly attributed. C. elegans molting larvae amyloid cuticle ABU/PQN innate immunity unfolded protein response Ecdysozoa, the clade of animals defined by the presence of an exoskeleton, exchange their cuticle during episodic molts...
Includes: Multimedia, Supplementary data