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Keywords: Alpha-synuclein
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Journal Articles

A novel 14-3-3θ phosphomimetic mouse model demonstrates social dominance defects

Open Access
In collection:
Fast & Fair peer review
Mary A. Gannon, Thanushri Srikantha, Rudradip Pattanayak, Navya Kapa, Aneesh Pathak, A. Claire Roberts, William J. Stone, Kasandra Scholz, Roschongporn Ekkatine, Talene A. Yacoubian
Journal: Biology Open
Biol Open (2025) 14 (6): bio061963.
https://doi.org/10.1242/bio.061963
Published: 10 June 2025
..., showed social dominance deficits. 14-3-3 Alpha-synuclein Tau Parkinson's disease Alzheimer's disease Phosphorylation Mouse models NMDA receptors National Institutes of Health http://dx.doi.org/10.13039/100000002 R01NS112203 Parkinson Association of Alabama...
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Includes: Supplementary data
Journal Articles

Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome

Open Access
Anila Iqbal, Marta Baldrighi, Jennifer N. Murdoch, Angeleen Fleming, Christopher J. Wilkinson
Journal: Biology Open
Biol Open (2020) 9 (10): bio054338.
https://doi.org/10.1242/bio.054338
Published: 5 October 2020
... and reproduction in any medium provided that the original work is properly attributed. Summary: Aggresomes of alpha-synuclein – the main component of the Lewy bodies in Parkinson's disease – prevent microtubule nucleation by the centrosome and inhibit cells, including olfactory neurons, from making cilia...
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Includes: Supplementary data