... guarantees substantial amounts of superior MenSCs with low passage number, but also is time efficient and economical. Adult stem cells Menstrual blood-derived endometrial stem cells Stem cell based therapy High-yield Red blood cell lysis Over the past decade, stem cell based therapies have...

...-dimensional SKP culture conditions. Skin-derived precursor cells Adult stem cells Acidic stress Multipotent Human fibroblast There is increasing interest in human skin-derived precursor (SKP) stem cells. These types of stem cells are multipotent and are present throughout adulthood...

... with increasing passages. A subset of the HGPS-naïve SKPs express progerin in vitro and in situ in HGPS skin sections. This is the first in vivo evidence that progerin is produced in adult stem cells, and implies that this protein could induce stem cells exhaustion as a mechanism contributing to aging. Our study...