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Keywords: Acidification
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Journal Articles
Kanin Salao, Lele Jiang, Hui Li, Vicky W.-W. Tsai, Yasmin Husaini, Paul M. G. Curmi, Louise J. Brown, David A. Brown, Samuel N. Breit
Journal:
Biology Open
Biol Open (2016) 5 (5): 620–630.
Published: 25 April 2016
..., then studied them in vitro and in vivo . We found phagocytosis triggered cytoplasmic CLIC1 translocation to the phagosomal membrane where it regulated phagosomal pH and proteolysis. Phagosomes from CLIC1 −/− BMDCs displayed impaired acidification and proteolysis, which could be reproduced if CLIC1...
Includes: Supplementary data
