Issues

Summary: The current study has revealed the phosphorylation-dependent dynamic nature of membrane association of SNAP-23 for mediation of different fusion steps in compound exocytosis from mast cells during allergen challenge.

Summary: The transcription factors Dlx3b and Dlx4b control the formation of early-born sensory hair cells or tether cells in the developing zebrafish inner ear.

Summary: Here we identified that Glucose transporter 4 (GLUT4) could interact with CHH binding protein (CHHBP) to regulate CHH-stimulated glucose release in Eriocheir sinensis.

Summary: This study provides the first qualitative and quantitative data on the occurrence of damage in the wings of the dragonfly Sympetrum vulgatum in nature. This article has an associated First Person interview with the first author of the paper as part of the supplementary information.

Summary: In contrast to many living organisms, storage fat is not beneficial for Dictyostelium cells when progressing through starvation and subsequent development of a dormant stage.

Summary: Our study documented how the relationship between variation in standard metabolic rate and growth is altered by the food availability in fish.

Summary: Targeting LncRNA DANCR obstructs triple negative breast cancer progression by down-regulating cancer stem cell marker CD44 and ABCG2.

Summary: This work provides the first comprehensive metabolomic of olive, which will provide new insights into understanding the olive metabolism and potentially help advance studies in olive metabolic engineering.

Summary: WASP-Arp2/3 regulates fusogen localization to intracellular vesicles in C. elegans embryos. Our results indicate that cell-cell fusions rely on distinct mechanisms at different developmental stages.

Summary: By examining the effects of the exopolysaccharide and environmental stress-related growth rate on Nostoc flagelliforme, this study gained insight into the morphogenesis of the colonial cyanobacterium.

Summary: The expression of Ldh-c in the skeletal muscle of plateau pika (Ochotona curzoniae) increases anaerobic glycolysis, resulting in enhanced sprint-running capacity and adaptation to a hypoxic environment.

Summary: Processed scaRNAs give rise to a novel regulatory RNP, which regulates the modification of ribosomal RNA. These findings provide insight into the mechanisms governing ribosome heterogeneity.

Summary: PQN-75 is expressed in pharyngeal gland cells and shares similarity with human basic salivary proline-rich protein PBR2, suggesting evolutionary conservation between gland cells in the upper digestive tract.

Summary: Genes involved in region-specific functions of the distal small intestine show distinct adaptive response following massive ileocecal resection in mice.

Summary: Adipocyte maturation restriction is tightly regulated by SIRT2 activation which downregulates preadipocytes from the maturation process as adaptation strategy in fish surviving in the polluted (hypoxic) environment.

Summary: This study reveals the architecture, molecular composition and dynamic expression profile of the extracellular matrix in ascidian embryos and larvae, providing clues for its function in chordate development.

Summary: This study developed a human experimental model for long-term studies using peritoneal tissue to evaluate integration with different materials, such as synthetic meshes.

Summary: Accelerometer data collected from captive fur seals and sea lions swimming were used to determine the best method for processing raw data to achieve the highest accuracy of stroke rate.