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Cover image
Cover Image
Cover: Germline-specific downregulation of Rtf1, the subunit of the chromatin remodeling Paf1 complex required for histone H2B modification, leads to severe defects in Drosophila germline differentiation, resulting in the arrested egg production and dramatically reduced ovary size (nanosGal4>UAS Rtf1 RNAi; nuclei are marked in green, magenta represents LaminC+Adducin). In response to stress, steroid-dependent miRNA let-7 regulates cellular identity of somatic escort cells, forming the germline differentiation niche that communicates with the germline via the cell adhesion-mediated Wingless (Wg) signaling. The Wingless pathway acts in the germline and establishes the specific chromatin status, promoting germline stem cell progeny differentiation. In particular, histone H2B monoubiquitination is delayed upon ecdysone/Wg deficit, postponing expression of differentiation genes required for the germline stem cell progeny to enter the differentiation program. Photo credit: Halyna R Shcherbata. See the article by König and Shcherbata. (doi: 10.1242/bio.201410553).
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Biologists @ 100 - join us in Liverpool in March 2025
We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate the Spring Meetings of the BSCB and the BSDB, the JEB Symposium Sensory Perception in a Changing World and a DMM programme on antimicrobial resistance. Find out more and register your interest to join us in March 2025 in Liverpool, UK.
There are many ways to produce goosebumps
In this Research Article, Jonathon McPhetres investigates the different stimuli that can produce goosebumps and how the body’s response is different depending on the trigger. This phenomenon highlights a shared trait with animals, suggesting that while goosebumps may seem less functional for humans, they reflect a complex interplay of physiological reactions. The author shows that goosebumps are more nuanced than previously thought.
Offering high-quality peer review through Review Commons
Did you know that BiO is an affiliate journal for Review Commons? This platform offers high-quality peer review of preprints before journal submission. This is just one of the many transfer options we offer to and from BiO. Read published articles that have come to us through this route in our Review Commons collection.
Reasons to submit to Biology Open
Discover the many reasons there are to publish in Biology Open. Biology Open prioritises making it easy for our authors by providing fast and fair decisions and rapid publication. Submissions are handled by expert Academic Editors covering a range of topics and trusted by our readers. Additionally, Biology Open strives to support our biological community.
How we support early-career researchers
Biology Open, its sister journals and its not-for-profit publisher, The Company of Biologists, support early-career researchers in numerous ways, helping them grow their network and raise their profile. Find out what we can do to support you.
