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Close ModalA starry pathway to the galaxy of HSP. The image shows a Hereditary Spastic Paraplegia patient-derived olfactory stem cell labelled for the cytoskeleton: actin (green), the organelles i.e. peroxisomes (red) and the nucleus (blue). Traditionally, rapid peroxisome movement has been shown to be dependent on microtubules available for transport. However, in Hereditary Spastic Paraplegia patients we hypothesize that the peroxisomes are taking an alternate route via actin (shown here) against microtubules, as acetylated α-tubulin is downregulated in these patient cells. See the article by Fan et al. (doi: 10.1242/bio.20147641). Photo credit: Gautam Wali.
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What should a Future Leader Review include?
Our Future Leader Reviews are an exclusive opportunity for early-career researchers who want to establish themselves in their field. We encourage you to be forward thinking in your approach, while providing a timely, balanced and accessible overview of the topic, including future prospects, challenges and questions.
Find out more and browse all the Future Leader Reviews published so far.
First person interview - Nicola Rossi
"…any initiative that helps connect researchers across the world is always worth considering."
PhD student Nicola Rossi tells us about his work with lizards, his future direction of research, and the importance of interaction and exposure for early-career researchers.
Meet the preLighters: Jonny Coates
A postdoc at Queen Mary University of London and an enthusiastic advocate for preprints, Jonny Coates talks about his journey into immunology, why he loves being a preLighter and his latest venture providing a positive and safe space for postdocs in the UK.
How to improve your scientific writing
A continuation of our recent overview on mastering the written word, Professor John Wallingford is back on the Node, this time emphasising the importance of gathering feedback on your writing and doing this early on in the process.
