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Cover image
Cover Image
A starry pathway to the galaxy of HSP. The image shows a Hereditary Spastic Paraplegia patient-derived olfactory stem cell labelled for the cytoskeleton: actin (green), the organelles i.e. peroxisomes (red) and the nucleus (blue). Traditionally, rapid peroxisome movement has been shown to be dependent on microtubules available for transport. However, in Hereditary Spastic Paraplegia patients we hypothesize that the peroxisomes are taking an alternate route via actin (shown here) against microtubules, as acetylated α-tubulin is downregulated in these patient cells. See the article by Fan et al. (doi: 10.1242/bio.20147641). Photo credit: Gautam Wali.
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A new Editor-in-Chief and new future for Biology Open
Find out more about the changes at the helm of Biology Open from departing Editor-in-Chief Steve Kelly and Director of The Company of Biologists Laura Machesky. The first Editorial from our new Editor-in-Chief Daniel Gorelick can be read here.
A Year at the Forefront Review
This A Year at the Forefront of Gliding Locomotion Review by Pranav C. Khandelwal, Mohamed A. Zakaria and John J. Socha looks closely at the complex interplay of anatomy, environment and adaptation in animals like flying snakes, dolphins and more.
Basement membrane dynamics and mechanics in tissue morphogenesis
Read one of our most recent Future Leader Reviews by Uwe Töpfer which provides an overview of the mechanisms by which Basement membranes can be remodeled to regulate the shape of tissues and organs.
Future Leader Reviews
BiO’s Future Leader Reviews help early-career researchers:
- Establish themselves in their field
- Find a foothold in a new area after a subject change post-PhD/postdoc
- Build their profile for grant, fellowship and job applications
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
