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Cover image
Cover Image
Wild type (left) and Bug22 mutant (right) Drosophila testes undergoing sperm individualization. Within individualizing cysts, highlighted by cleaved caspase-3 staining in red, migrating individualization complexes (luminal green structures stained by F-actin) can be observed. These machineries appear at the base of the cyst, next to sperm heads (DAPI staining, in blue), along the cyst, forming cystic bulges, or else close to the testis apex, where they take the configuration of voluminous waste bags. Cystic bulges and waste bags are highly defective in the Bug22 mutant testis. See the article by Maia et al. (doi:10.1242/bio.20146577).
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