Issues
-
Cover image
Cover Image
Planarian flatworms have the remarkable capacity to regenerate their entire body. Despite a wealth of molecular-genetic data, no constructive model of regenerative patterning exists. Levin and colleagues (doi:10.1242/bio.20123400) created a formalism for abstracting key features of flatworm anatomy from functional experimental data; an example of this graph representation is shown here superimposed upon successive stages of head regeneration in an amputated worm. New artificial intelligence tools can use the formalism and database to help derive algorithmic models of regeneration, establishing a new bioinformatics of shape.
- PDF Icon PDF LinkTable of contents
RESEARCH ARTICLE
Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier
Advertisement
A new Editor-in-Chief and new future for Biology Open

Find out more about the changes at the helm of Biology Open from departing Editor-in-Chief Steve Kelly and Director of The Company of Biologists Laura Machesky. And read our interview with new Editor-in-Chief Daniel Gorelick.
A Year at the Forefront of Plasmodesmal Biology

Andrea Paterlini presents a short overview of recent discoveries, innovations, community resources and hypotheses in the field of plasmodesmata biology.
Future Leader Review: Glial plasticity at nervous system transition zones

In our most recent Future Leader Review, Laura Fontenas from Florida Atlantic University highlights recent work on glial cell migration in and out of the spinal cord.
Future Leader Reviews
Our Future Leader Reviews help early-career researchers:
- Establish themselves in their field
- Find a foothold in a new area after a subject change post-PhD/postdoc
- Build their profile for grant, fellowship and job applications
Sustainable Conferencing Initiative

Through our Sustainable Conferencing Grants, we promote the use of new technology and greener modes of travel. Our blog posts showcase examples of sustainability in action and share experience about how new technologies and conference formats work in practice.