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RESEARCH ARTICLES
Insights into Octopus maya cathepsins from metatranscriptome and genome: structure evolutionary relationships and functional role prediction in digestive processes
Summary: Comprehensive genomic and transcriptomic analysis of Octopus maya proteases reveals evolutionary insights, structural diversity, and potential applications for optimizing protein digestion and sustainable aquaculture practices.
Adaptive evolution of cytochrome b in songbirds
Summary: The accelerated evolution of the bc1 complex in songbirds resulted in clusters of songbird-specific cytochrome b substitutions of functional residues, allowing for a reduction of superoxide generation.
Morphlight theory inspired by raptors: musculoskeletal modeling and muscle control in Falco peregrinus wing flapping
Summary: Musculoskeletal modeling and muscle control in Falco peregrinus wing flapping. This study elucidated the function of specific wing muscles in F. peregrinus, establishing a novel methodology for raptor muscle research.
Differential effect of ubiquitous and germline depletion of Integrator complex function on C. elegans physiology
Summary: Integrator has emerged as a critical protein complex for metazoan development. In this study, we used the auxin–degron system to explore tissue and temporal requirement of the Integrator in C. elegans development and aging.
The zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis
Summary: This study investigates the role of the ETS transcription factor Fli1b in regulating hematopoiesis in zebrafish embryos. fli1b mutants show reduced erythropoiesis and myelopoiesis, which is compensated by increased myeloid marker expression at the alternative hematopoietic site, the endocardium.
trithorax is an essential regulator of cardiac Hox gene expression and anterior-posterior patterning of the Drosophila embryonic heart tube
Summary: The COMPASS-like histone methyltransferase trithorax regulates proper cardiac cell division and is required for collinear Hox expression which patterns the anterior-posterior axis of the Drosophila heart tube.
Unpredictable aggressive defence of the venomous snake, Crotalus ravus, towards predators and humans
Summary: Venomous snakes may respond with aggressive defence towards predators. Knowledge of their antipredation behaviour helps elucidate their decision-making during interspecific encounters, including with humans.
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Interviews with Biologists @ 100 conference speakers

Explore our interviews with keynote speakers from the Biologists @ 100 conference, hosted to celebrate our publisher’s 100th anniversary, where we discuss climate change and biodiversity with Hans-Otto Pörtner and Jane Francis, health and disease with Charles Swanton and emerging technologies with Manu Prakash and Jennifer Lippincott-Schwartz.
Daniel Gorelick on Open Access and Read & Publish in Biology Open
Editor-in-Chief, Daniel Gorelick, talks about Biology Open, the importance of Open Access publishing and how The Company of Biologists’ Read & Publish initiative benefits researchers.
A novel role for glycogen synthase during heat stress

Pratibha Bhadauriya, Akanksha Onkar and colleagues highlight a novel role for glycogen synthase (GS) in regulating autophagy during heat stress via heat shock factor 1 in neuronal cells. Moreover, they show that GS-mediated glycogen metabolism is not only a reservoir of energy but an active molecular player in heat stress responses.
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Biology Open, its sister journals and its not-for-profit publisher, The Company of Biologists, support early-career researchers in numerous ways, helping them grow their network and raise their profile. Find out what we can do to support you.