Issues
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Cover image
Cover Image
An image of the tardigrade Hypsibius exemplaris, from the paper by Quiroga-Artigas and Moriel-Carretero. This image was captured after staining the animal with a live dye (MemBrite Cell Surface Staining Kit). The dye enhances the cuticle and inner body structures, providing a unique 3D visualisation of tardigrade morphology through a confocal microscope. Creative Commons Attribution 4.0 International license.
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EDITORIAL
MEETING REVIEWS
Beyond barriers, towards diversity: how hybrid student conferences can drive accessibility
Summary: This Meeting Review presents conclusions from the third International Student Symposium on Animal Behaviour and Cognition (ISSABC), an international hybrid conference organised by ECRs that aimed to provide a larger, international stage for ECRs to present their research and network.
Young minds, deeper insights: a recap of the BMAS Summer School 2023, ranging from basic research to clinical implications of bone marrow adipose tissue
Summary: Given the growing interest in bone marrow adiposity (BMA), the International Bone Marrow Adiposity Society (BMAS) Summer School 2023 was envisioned to share advancements on BMA, and offer advice on career development to early-career investigators.
REVIEW
The salamander limb: a perfect model to understand imperfect integration during skeletal regeneration
Summary: This Review explores the progress and new advances in the salamander skeletal biology field, focusing on how the limb skeleton is efficiently regenerated upon amputation or injury.
RESEARCH ARTICLES
A Drosophila model of mitochondrial disease phenotypic heterogeneity
Summary: This study uses Drosophila to model the symptomatic variability in mitochondrial disease and provides mechanistic insight into the effects of weak and strong complex I deficiency in the brain.
Protein complexes from mouse and chick brain that interact with phospho-KXGS motif tau/microtubule associated protein antibody
Summary: Immunoprecipitation (IP), mass spectrometry and immunofluorescence were used to identify potential direct and indirect binding partners of phospho-KXGS motif tau/microtubule associated protein antibody.
Storage cell proliferation during somatic growth establishes that tardigrades are not eutelic organisms
Summary: This study demonstrates active storage cell proliferation in tardigrade post-embryonic development. Storage cells replicate in bursts during molting, especially in juveniles, and DNA replication disruption induces molting-related fatalities.
MiR-145-5p overexpression rejuvenates aged adipose stem cells and accelerates wound healing
Summary: MiR-145-5p is decreased in adipose-derived stem cells (ADSCs) from the old donors (O-ADSCs), compared to that from young donors (Y-ADSCs). MiR-145-5p overexpression could promote O-ADSCs proliferation and migration, and further enhance their therapeutic effect for wound healing.
Novel therapeutic targets, including IGFBP3, of umbilical cord mesenchymal stem-cell-conditioned medium in intrauterine adhesion
Summary: Eleven mRNAs were discovered to be the underlining intervention targets of UCMSCs-CM on intrauterine adhesion, which are of great significance for potential diagnosis and treatment.
Thermal tolerance in an extremophile fish from Mexico is not affected by environmental hypoxia
Summary: Sulphur fish live in oxygen-free waters in Mexico with temperatures often higher than 35°C. They can tolerate temperatures up to 43.2°C and, at least in one species, the thermal tolerance is not affected by hypoxia.
METHODS & TECHNIQUES
Automated counting of Drosophila imaginal disc cell nuclei
Summary: A set of pipelines for ImageJ/Fiji that performs fast and accurate automatic nuclei counts in Drosophila imaginal discs.
FIRST PERSON
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Daniel Gorelick on Open Access and Read & Publish in Biology Open
Editor-in-Chief, Daniel Gorelick, talks about Biology Open, the importance of Open Access publishing and how The Company of Biologists’ Read & Publish initiative benefits researchers.
A new model for cephalopod neurobiology
Fabián Vergara-Ovalle and colleagues show the distribution of the nitric oxide system within the nervous system, particularly in areas associated with olfactory and visual information processing, in Octopus maya. Since these octopi can be cultured in the lab, they represent a valuable model for studying cephalopod neurobiology.
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