Issues

Summary: This Review examines drug resistance in colorectal cancer, focusing on the role of nutrient depletion in multidrug resistance. It highlights metabolic adaptations, and the role of MDR1/P-glycoprotein, and suggests innovative strategies to counteract resistance.

Summary: This study investigates cortisol responses in zebrafish larvae to acute stress, revealing a rapid feedback loop and the glucocorticoid receptor's role, offering insights for future research in stress biology.

Summary: Budgerigars exhibit individual variability in associations between song notes and body movements during courtship. This suggests the possible influence of learning on multimodal courtship displays.

Summary: We provide evidence that a hybrid line of koi carp × goldfish is characterized by expression of mRNA from genes responsible for synthesis of ethanol and consequently for anoxia tolerance.

Summary: This research conducts a systematic research to identify the roles of both common and unique COMPASS subunits in Drosophila heart development.

Summary: Social interactions among ants are impacted by food availability and group size but not by food type.

Summary: In the context of age-related neurodegeneration in Drosophila, changes in three mitochondrial reactive oxygen species in the brain are related to altered survival in varied and unexpected ways.

Summary: Older Spiny mice took longer to regenerate ear wounds with less cartilage and fewer adipocytes. All regenerated tissue had less cartilage and muscle than uninjured tissue, declining proximal to distal.

Summary: Human pluripotent stem cell (hPSC)-derived lung progenitors were isolated using CD166 and differentiated into airway epithelial cells. These hPSC-derived airway epithelial cells were then shown to be useful for studying respiratory infections, such as Influenza A.

Summary: We study, for the first time in liolaemid lizards, the effects of blood extraction and thermal and locomotor performance experiments on stress in Liolaemus attenboroughi as a model species.

Summary: We sought to identify odorant molecules that could have triggered behavioural discrimination of cancerous mice, we show that volatile organic compounds may only partly be involved in mice cancer discrimination.

Summary: The study demonstrates the effectiveness of anti-CoA antibodies in analysing protein CoAlation, particularly in immunofluorescent assay, and confirms a significant increase in protein CoAlation in response to oxidative stress.

Summary: Using six species of tardigrade we observe that thermal tolerance varies by species, and consistent with previous work we find that anhydrobiosis increases thermal tolerance relative to hydrated/active conditions.