Issues
-
Cover image
Cover Image
A selection of covers from Professor Steven Kelly’s time as Editor-in-Chief of Biology Open. Image licensed by a Creative Commons Attribution 4.0 International license.
- PDF Icon PDF LinkTable of contents
- PDF Icon PDF LinkIssue info
EDITORIALS
REVIEWS
No-cost meals might not exist for insects feeding on toxic plants
Summary: Detection of physiological and ecological costs of chemical defence in insects under an ecophysiological framework for the better understanding of the ecology and evolution of plant-insect-antagonist interaction.
Maintenance of neuronal fate and transcriptional identity
Summary: This Review explores recent progress in understanding the mechanisms that maintain neuronal cell fate and gene expression, discussing the activating and repressive factors involved, relevance to disease, and outstanding questions.
RESEARCH ARTICLES
Loss of flrt2 gene leads to microphthalmia in zebrafish
Summary: flrt2 is necessary for the normal development of the zebrafish eyes since it is strongly expressed in the retina and deletion of flrt2 causes microphthalmia in zebrafish
An ethogram identifies behavioural markers of attention to humans in European herring gulls (Larus argentatus)
Summary: Urbanised herring gulls successfully benefit from anthropogenic food sources. We show that human food-centred behaviours directly modulate the attentional states of such gulls.
Transcriptome analysis reveals an Atoh1b-dependent gene set downstream of Dlx3b/4b during early inner ear development in zebrafish
Summary: Identification of various new gene sets regulated by the transcription factors Dlx3b/4b during early inner development in zebrafish.
Tbx5 overexpression in embryoid bodies increases TAK1 expression but does not enhance the differentiation of sinoatrial node cardiomyocytes
Summary: The sinoatrial node transcriptional program is activated by blocking phosphorylation of TAK1 during cardiac differentiation of pluripotent cells, providing a simplified protocol for the in vitro differentiation of cardiac pacemakers.
The insulin receptor regulates the persistence of mechanical nociceptive sensitization in flies and mice
Summary: This paper demonstrates a conserved role for the insulin receptor in regulating the persistence of injury-induced mechanical nociception in flies and mice.
METHODS & TECHNIQUES
Ac/Ds transposition for CRISPR/dCas9-SID4x epigenome modulation in zebrafish
Summary: The Ac/Ds transposition system, which enables the continuous expression of guide RNAs for CRISPR/Cas perturbation, is adapted to examine the epigenome in zebrafish.
A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB
Summary: We report that a broadly used rabbit monoclonal antibody raised against human EZH2 cross-reacts with Scaffold Attachment Factor B in mouse embryonic stem cells under buffer conditions that are commonly used for chromatin immunoprecipitation.
FIRST PERSON
Advertisement
Fast & Fair peer review

We have recently launched the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. To learn more about our progress and future plans, read the Editorial by our Editor-in-Chief Daniel Gorelick or visit the Fast & Fair peer review page.
Interviews with Biologists @ 100 conference speakers

Explore our interviews with keynote speakers from the Biologists @ 100 conference, hosted to celebrate our publisher’s 100th anniversary, where we discuss climate change and biodiversity with Hans-Otto Pörtner and Jane Francis, health and disease with Charles Swanton and Sadaf Farooqi, and emerging technologies with Manu Prakash and Jennifer Lippincott-Schwartz.
Daniel Gorelick on Open Access and Read & Publish in Biology Open
Editor-in-Chief, Daniel Gorelick, talks about Biology Open, the importance of Open Access publishing and how The Company of Biologists’ Read & Publish initiative benefits researchers.
A novel role for glycogen synthase during heat stress

Pratibha Bhadauriya, Akanksha Onkar and colleagues highlight a novel role for glycogen synthase (GS) in regulating autophagy during heat stress via heat shock factor 1 in neuronal cells. Moreover, they show that GS-mediated glycogen metabolism is not only a reservoir of energy but an active molecular player in heat stress responses.
How we support early-career researchers

Biology Open, its sister journals and its not-for-profit publisher, The Company of Biologists, support early-career researchers in numerous ways, helping them grow their network and raise their profile. Find out what we can do to support you.