Issues

Summary: Parvatam and colleagues elaborate on India's first meeting focused on Microphysiological Systems and how they hope to usher in a new era of 3D biology in the country.

Summary: This a Year at the Forefront Review sheds light on the most recent developments in the field of bacterial responses and defenses against reactive oxygen and chlorine species

Summary: This study uses Golgi disorganisation in non-adherent cells to test how differential Arf1 activation and kinetics of Arf1 inactivation could regulate Golgi organisation and function.

Summary: Distinct metabolic alterations in neuronal progenitors at different stages of maturation during ZIKV infection may explain the pathophysiology over each trimester and highlight a therapeutic potential of metabolic remodelling.

Summary: Quantitative analysis of the pseudostratified airway epithelium reveals basal stem cells and their stress fibers remodel during an unjamming transition.

Summary: Zebrafish and turquoise killifish are complementary models for aging studies. Aging reduced angiogenesis in regenerating caudal fin and anti-angiogenic pharmacological treatment reduced regeneration of aged caudal fin.

Summary: Cell density affects preferred metabolic pathway of prostate cancer cells, leading to CSC-like characteristics.

Summary: The relevance of mitochondria-lysosome membrane contact sites dysfunction as a primary event in axonopathies etiology, and as a key signaling hub opening novel therapeutic strategies in peripheral neuropathies, especially in Charcot-Marie-Tooth disease.