Issues

Summary: This A Year at the Forefront Review summarises key findings and new datasets in the intersection of proteostasis and aging, with a focus on articles and preprints published between November 2021 and October 2022.

Summary: This review aims to consider the reciprocal relationship between the Golgi, cilium and ECM in tissue biology and highlights the need for more integrated studies in this field.

Summary: Amoeba proteus exhibits dorsoventral asymmetric membrane dynamics during pressure-driven amoeboid locomotion.

Summary: No evidence found for the impact of handling duration on constitutive innate immune function in breeding Adélie penguins.

Summary: We present a new open source, deep learning-enabled tool, Mouse Embryo Multi-Organ Segmentation (MEMOS), to estimate the segmentation of 50 anatomical structures from microCT scans of embryonic mice.

Summary: Although multiple phenotypic traits have evolved in cane toads across their invaded range in Australia, divergences among toads in skin bacterial communities are more affected by local environments than by evolved shifts in the hosts.

Summary: Despite evidence that secreted cAMP is widely used by most Dictyostelia to control morphogenesis and cell differentiation, Polysphondylium violaceum does not require genes responsible for detection, synthesis and degradation of secreted cAMP

Summary: This study revealed that the regeneration-response enhancers are composed of two transcription factor-binding motifs. Two activating signals evoked by the injuries ensure the fidelity of gene response.

Summary: Using GPS telemetry, we mapped the home ranges and flight patterns of Pteropus giganteus males in southern India. We hope these data will also help conservation efforts.