Issues

Summary: This Meeting Review highlights the latest trends in bioimaging discussed at the Third Imabio YSN Conference 2022 in Lyon which was organized by and dedicated to early-career young scientists.

Summary: Endothelial actin structures and actin-mediated force generation coordinate the multi-step angiogenic process.

Summary: We review recent progress in natural killer (NK) cells for cancer immunotherapy, from the basics of NK cell biology to chimeric antigen receptor-transduced NK cell applications.

Summary: This research shows the effect of sevoflurane anesthesia just after learning on amnesia and that sevoflurane inhibits neuronal ensemble activity in hippocampal CA1.

Summary: Mutant shox2 fish display behaviors associated with vestibular deficits, show reduced number of anterior statoacoustic ganglion neurons that innervate the utricle and have altered otic cell populations defined by single cell RNA-seq.

Summary: A genome-wide CRISPR screen reveals a role for TMEM30A-regulated membrane asymmetry in governing cancer cell sensitivity to ceramide-induced cell death.

Summary: This study assigns alpha-T-catenin to a new tissue and cell-type with implications for its growing disease linkages.

Summary: In vivo modelling of tumor cell lung colonization reveals NSCLC histopathology-selective metastatic capabilities.

Summary: Using a dual depletion approach, i.e., combining auxin-inducible degradation with RNAi, we show that LIN-12 is not required for proliferation of the C. elegans anchor cell following EGL-43 loss.

Summary: Zebrafish embryos can hatch early if they sense chemical or mechanical indicators of predation risk, but when they hatch early they are poorly developed and more vulnerable to predators as larvae.

Summary: ECM remodelling plays a role in the maintenance of intestinal stem cells and crypt morphology during development and in the adult mouse gut.

Summary: We present a software tool for automatic cell segmentation of fluorescent cancer cells in zebrafish larvae to determine characteristics of the cancer cell population on a single-cell basis