Issues
-
Cover image
Cover Image
The image shows the expression of the gene Rhbg detected by in situ hybridisation on gills dissected from the fish Alcolapia alcalica. This gene codes for an ammonia transporter and is nevertheless robustly expressed in the gill filaments of a fish that excretes most of its nitrogenous waste as urea. See the paper by White and colleagues for details.Image licensed under a Creative Commons Attribution 4.0 International license.
- PDF Icon PDF LinkIssue info
EDITORIAL
MEETING REVIEW
Neural stem cell research in Africa: current realities and future prospects
Summary: A review of stem cell research on the brains of animals in Africa.
SPECIAL ARTICLE
Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world
Summary: Euglenoids show great promise to benefit our world; as biofuels, robotics design simulators, anti-cancer and food nutritional agents, but the absence of reference genomes currently limit realizing these benefits.
RESEARCH ARTICLES
Correlative light and electron microscopy reveals fork-shaped structures at actin entry sites of focal adhesions
Summary: We reveal and quantitatively assess a novel fork structure in focal adhesions using correlative fluorescence and electron microscopy
Targeting Drosophila Sas6 to mitochondria reveals its high affinity for Gorab
Summary: A method for relocalizing proteins from the Golgi or centrosomes to the mitochondria in Drosophila cells is used to investigate the affinities of these proteins for each other.
NEDD1-S411 phosphorylation plays a critical function in the coordination of microtubule nucleation during mitosis
Summary: The regulation of NEDD1 phosphorylation at S411 is essential for the coordination of the centrosomal and acentrosomal microtubule nucleation pathways and spindle assembly in mitotic cells.
PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones
Summary: In contrast to previous mechanistic models about heterotypic cell competition, not all experimental conditions require PTP10D to eliminate polarity-deficient clones.
Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills
Summary: Two closely related extremophile fish species adapted to excrete urea display differential expression of ammonium transporter in gills.
Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit
Summary: We identified two phosphosites (S11 and S36) in the yeast centrosome component Spc110 from maternal origin and found that these phosphosites control timely cell cycle progression.
Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner
Summary:Drosophila hemocytes recognized disintegrated basement membrane of the LG tumors overexpressing MMP2 and stimulated ROS production to induce the anti-tumor peptides under innate immune pathway in the fat body.
Postnatal depletion of maternal cells biases T lymphocytes and natural killer cells’ profiles toward early activation in the spleen
Summary: After specific depletion of maternal cells in neonates using diphtheria toxin receptor transgenic mice, early activation of splenic T and natural killer cells was observed.
Pavlovian conditioning of gentoo penguins (Pygoscelis papua) to underwater sound
Summary: Penguins were trained to pair underwater sound with fish. Our results indicate that sounds may serve as important cues for diving penguins and other sea birds.
METHODS & TECHNIQUES
Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo
Summary: We introduce transgenic and software tools to measure tensions across the outer and inner nuclear envelope in mice. These tools facilitate our ability to test mechanotransduction hypotheses in vivo.
FIRST PERSON
CORRECTION
Advertisement
Biologists @ 100 - join us in Liverpool in March 2025
We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate the Spring Meetings of the BSCB and the BSDB, the JEB Symposium Sensory Perception in a Changing World and a DMM programme on antimicrobial resistance. Find out more and register your interest to join us in March 2025 in Liverpool, UK.
There are many ways to produce goosebumps
In this Research Article, Jonathon McPhetres investigates the different stimuli that can produce goosebumps and how the body’s response is different depending on the trigger. This phenomenon highlights a shared trait with animals, suggesting that while goosebumps may seem less functional for humans, they reflect a complex interplay of physiological reactions. The author shows that goosebumps are more nuanced than previously thought.
Offering high-quality peer review through Review Commons
Did you know that BiO is an affiliate journal for Review Commons? This platform offers high-quality peer review of preprints before journal submission. This is just one of the many transfer options we offer to and from BiO. Read published articles that have come to us through this route in our Review Commons collection.
Reasons to submit to Biology Open
Discover the many reasons there are to publish in Biology Open. Biology Open prioritises making it easy for our authors by providing fast and fair decisions and rapid publication. Submissions are handled by expert Academic Editors covering a range of topics and trusted by our readers. Additionally, Biology Open strives to support our biological community.
How we support early-career researchers
Biology Open, its sister journals and its not-for-profit publisher, The Company of Biologists, support early-career researchers in numerous ways, helping them grow their network and raise their profile. Find out what we can do to support you.