Summary: A review of stem cell research on the brains of animals in Africa.
Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world
Summary: Euglenoids show great promise to benefit our world; as biofuels, robotics design simulators, anti-cancer and food nutritional agents, but the absence of reference genomes currently limit realizing these benefits.
Correlative light and electron microscopy reveals fork-shaped structures at actin entry sites of focal adhesions
Summary: We reveal and quantitatively assess a novel fork structure in focal adhesions using correlative fluorescence and electron microscopy
Summary: A method for relocalizing proteins from the Golgi or centrosomes to the mitochondria in Drosophila cells is used to investigate the affinities of these proteins for each other.
NEDD1-S411 phosphorylation plays a critical function in the coordination of microtubule nucleation during mitosis
Summary: The regulation of NEDD1 phosphorylation at S411 is essential for the coordination of the centrosomal and acentrosomal microtubule nucleation pathways and spindle assembly in mitotic cells.
PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones
Summary: In contrast to previous mechanistic models about heterotypic cell competition, not all experimental conditions require PTP10D to eliminate polarity-deficient clones.
Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills
Summary: Two closely related extremophile fish species adapted to excrete urea display differential expression of ammonium transporter in gills.
Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit
Summary: We identified two phosphosites (S11 and S36) in the yeast centrosome component Spc110 from maternal origin and found that these phosphosites control timely cell cycle progression.
Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner
Summary:Drosophila hemocytes recognized disintegrated basement membrane of the LG tumors overexpressing MMP2 and stimulated ROS production to induce the anti-tumor peptides under innate immune pathway in the fat body.
Postnatal depletion of maternal cells biases T lymphocytes and natural killer cells’ profiles toward early activation in the spleen
Summary: After specific depletion of maternal cells in neonates using diphtheria toxin receptor transgenic mice, early activation of splenic T and natural killer cells was observed.
Summary: Penguins were trained to pair underwater sound with fish. Our results indicate that sounds may serve as important cues for diving penguins and other sea birds.
METHODS & TECHNIQUES
Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo
Summary: We introduce transgenic and software tools to measure tensions across the outer and inner nuclear envelope in mice. These tools facilitate our ability to test mechanotransduction hypotheses in vivo.