Summary: With this manuscript, we aim to increase the awareness on research culture, and illustrate that a well developed research culture can positively influence scientific developments.
Chk2-p53 and JNK in irradiation-induced cell death of hematopoietic progenitors and differentiated cells in Drosophila larval lymph gland
Summary: Irradiation-induced cell death in larval lymph gland requires Drosophila ATM, Chk2, p53, and reaper in hematopoietic progenitors, while it involves Drosophila ATM, JNK, and reaper in differentiated blood cells.
20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun
Summary: During Drosophila dorsal closure, 20E signaling acts non-canonically through an interaction between EcR and the AP-1 subunit, Jun, to control gene expression at regions containing AP-1 motifs but no EcREs.
Developmental expression patterns of toolkit genes in male accessory gland of Drosophila parallels those of mammalian prostate
Summary: We show genetic toolkit conservation between Drosophila MAG and mammalian prostate may suggest a common modular developmental design.
A mouse model displays host and bacterial strain differences in Aerococcus urinae urinary tract infection
Summary:Aerococcus urinae clinical isolates are genetically diverse and display differential capacity to cause UTI in a mouse model. Infection was rapidly cleared from the bladder, but persisted and caused inflammation in the kidney.
Twitchy, the Drosophila orthologue of the ciliary gating protein FBF1/dyf-19, is required for coordinated locomotion and male fertility
Summary: Primary cilia are compartmentalised from the rest of the cell by a molecular gate. We show that the Drosophila orthologue of a molecular gate protein functions in both compartmentalised sensory cilia and ‘cytosolic’ sperm flagella.
Summary: The study reports a series of experiments aimed at understanding the orientation mechanisms of Arabian camels in the Rub' al Khali desert in the UAE. Camels were taken either on foot or inside trucks to unfamiliar release points, some 6 km from their living pens. Camels homed successfully after simple displacements but seemed lost after a looping journey. It is inferred that camels use path integration, dead reckoning, after short simple displacements.
Summary: The present study provides increased understanding of the energetic costs faced by bats in thermally challenging environments along an environmental temperature gradient.
METHODS & TECHNIQUES
Summary: We developed an adaptable mass spectrometry-based assay to assess the differentiation potential of human neural stem cells.