Issues
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Cover image
Cover Image
An image of opercular epithelium of a mummichog (Fundulus heterociltus), exhibiting cell-specific distribution of Claudin-10c (Cldn-10c, yellow) and Na+-K+-ATPase (NKA, red) following acclimation to hypersaline water from a paper by Chun Chih Chen and colleagues. Intense Cldn-10c immunoreactivity in the apical crypt area of NKA-rich opercular epithelium ionocytes contribute to the idea that Cldn-10 proteins play a key role in paracellular cation pore formation and sodium shunt function within marine fish branchial tissues. Image licensed under a Creative Commons Attribution 4.0 International license.
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RESEARCH ARTICLES
Variations in oxidative stress and antioxidant defense level during different phases of hibernation in common Asian toad, Duttaphrynus melanostictus
Summary: Hibernation though a period of metabolic depression in common Asian toad, we found oxidative stress and augmented antioxidant defense both during hibernation and arousal from hibernation and coming down of these parameters to basal level during post arousal phase.
Pressure-induced changes on the morphology and gene expression in mammalian cells
Summary: Application of high hydrostatic pressure on somatic cells induce changes in gene expression including upregulation in pluripotency genes.
Mummichog gill and operculum exhibit functionally consistent claudin-10 paralog profiles and Claudin-10c hypersaline response
Summary: The role of claudin-10 tight junction proteins in paracellular salt secretion across fish branchial epithelia is indicated by organ-specific responses to hyperosmotic conditions and their association with salt secreting transcellular proteins
High-throughput detection of eukaryotic parasites and arboviruses in mosquitoes
Summary: We describe a surveillance technique enabling the detection of known and previously uncharacterized pathogens present in mosquitoes. This approach could reduce the costs of vector-borne disease monitoring and provide early warning of emerging diseases.
Muscle forces and the demands of human walking
Summary: A musculoskeletal model of human walking reveals the consistency, timing, and magnitude of lower limb muscle forces across the stance phase.
The dorsal blastopore lip is a source of signals inducing planar cell polarity in the Xenopus neural plate
Summary: The blastopore lip contains a cue that induces the progressive establishment of planar polarity in the neural plate in the posterior to anterior direction.
Rab7 is required for mesoderm patterning and gastrulation in Xenopus
Summary: The late endosomal regulator Rab7 is required for gastrulation movements and axis elongation in Xenopus by regulating early mesoderm patterning.
Morphological mechanism allowing a parasitic leech, Ozobranchus jantseanus (Rhynchobdellida: Ozobranchidae), to survive in ultra-low temperatures
Summary: The freeze tolerance mechanism of Ozobranchus jantseanus, the largest metazoan animal requiring no pretreatment that can survive in ultra-low temperature, was first studied from the perspective of morphology.
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