Summary: Recent findings that germline and stem cell specification may differ between species may have important implications for regenerative medicine and the future of stem cell biology.
Summary: Pom152 is a transmembrane nucleoporin important for nuclear pore complex structure and synthesis. Here we further characterize Pom152, showing that the cytosolic and transmembrane domains are sufficient for NPC localization.
Summary: The current findings provide the basis for individualized ototherapeutics that manipulate surviving cellular elements in order to bias cochlear function towards normal hearing even in the presence of dead cells.
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network
Summary: The Golgi protein GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network. We also identify a GRASP55 proximal interactome enriched at the ER-Golgi interface.
Summary: This research paper focuses on the dorsal chromatic variations in Mediterranean lizards, analysing the effect of seasonality and ontogeny.