Biology Open (BiO) is an Open Access journal that supports the community of biologists through the publication of peer-reviewed original research across all aspects of the biological sciences. We aim to provide rapid peer review and publication of scientifically sound results and conclusions, without a requirement for perceived impact. BiO also aspires to promote a peer-review system that is timely, thorough, constructive and fair.
Authors are encouraged to submit work of appropriate scope directly to BiO. Editorial decisions are made by an international board of research-active academic Editors, led by Editor-in-Chief Steven Kelly and supported by Deputy Editors Cathy Jackson and Yishi Jin.
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Supporting early-career researchers
As a journal published by The Company of Biologists, BiO champions early-career researchers. We publish First Person interviews from first authors of our research papers, provide funds to sponsor early-career meetings, and create career development opportunities through our Meeting Reviews and Future Leader Reviews programs. Find out more about the practical solutions available to help this vital community navigate the first stages of their careers.
KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance by Solenne Gaillard, Virginie Charasson, Cyril Ribeyre, Kader Salifou, Marie-Jeanne Pillaire, Jean-Sebastien Hoffmann, Angelos Constantinou, Didier Trouche and Marie Vandromme
KDM5A and KDM5B histone-demethylases contribute to hydroxyurea-induced replication stress tolerance, in part by regulating expression of ribonuclease reductase subunit RRM2.
Quantitative analysis of signaling responses during mouse primordial germ cell specification by Sophie M. Morgani and Anna-Katerina Hadjantonakis
A subpopulation of pluripotent cells of the embryo give rise to the primordial germ cells (PGCs), the precursors of the sperm and egg. To determine how PGCs are first segregated from the soma, the authors investigated BMP, MAPK and WNT signaling over time in PGCs and their surrounding niche in vitro and in vivo at single-cell resolution.